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为了解以祛痰活血、开窍醒脑组方的脑脉Ⅱ号中药制剂对缺血的脑组织的影响，本实验将１４只大鼠分正常组、急性脑缺血模型组和脑脉Ⅱ号＋脑缺血组，脑缺血动物模型以结扎双侧颈总动脉合并血压下降法制备。电镜观察结果显示：正常组大脑皮层神经细胞、胶质细胞、毛细血管形态结构正常。模型组可见神经细胞肿胀，胞膜、核膜严重破损，胞质水肿，线粒体肿胀；胶质细胞病变严重；毛细血管管腔变窄，管壁粗糙。脑脉Ⅱ号＋脑缺血组神经细胞形态结构接近正常；胶质细胞轻度肿胀，胞质无明显水肿空白区域；毛细血管结构也基本正常。结果从组织形态学角度提示，祛痰活血、开窍醒脑中药能减轻脑缺血大鼠大脑皮层神经组织的损害，对脑组织的缺血性损伤有明显的保护作用
In order to understand the effect of expectorant and activating blood, recuperate Xingnao Xingnao formula on the brain tissue of ischemic brain tissue in rats, 14 rats were divided into normal group, acute cerebral ischemia group and cerebral vein Ⅱ + Cerebral ischemia group, cerebral ischemia model was established by ligation of both common carotid arteries and blood pressure reduction. Electron microscopy results showed that: normal group of cerebral cortex neurons, glial cells, capillaries morphology is normal. The model group showed swelling of the nerve cells, severe damage of the cell membrane and nuclear membrane, cytoplasmic edema and swelling of the mitochondria; serious glial cell lesions; narrowing of the capillary lumen and rough wall. Cerebral artery Ⅱ + cerebral ischemia group nerve cell morphological structure close to normal; mild glial swelling, cytoplasm no obvious edema blank area; capillary structure is also normal. Results Histopathology suggested that expectorant and activating blood and activating resuscitation and recuperating can reduce the damage of nerve tissue in the cerebral cortex of rats with cerebral ischemia and have obvious protective effect on ischemic injury of brain