脑积水现代外科治疗的重要措施之一是用导管置于侧脑室,将脑脊液引流入血液循环、腹腔或输尿管中。导管长期存留体内极易发生菌血症。细菌作为抗原可刺激机体免疫系统产生抗体,抗原和抗体在一定条件下形成可溶性免疫复合物而沉积于肾组织。这种由脑脊液分流感染所造成的肾脏损害称为“分流性肾炎”(Shunt Nephritis)。 1965年Black等报告2例脑脊液分流后长期存在白色葡萄球菌菌血症所致的肾病综合征,此后有 One of the important measures of modern surgical treatment of hydrocephalus is to place the catheter in the lateral ventricle and drain the cerebrospinal fluid into the blood circulation, the abdominal cavity or the ureter. Catheter long-term retention of the body prone to bacteremia. Bacteria as an antigen can stimulate the body’s immune system to produce antibodies, antigens and antibodies under certain conditions, the formation of soluble immune complexes deposited in the kidney. This kidney damage caused by CSF shunt infection is called “Shunt Nephritis.” 1965 Black et al reported 2 cases of cerebrospinal fluid shunt long-term presence of Staphylococcus aureus bacteremia caused by nephrotic syndrome, since