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作者以前曾介绍一种用层析法纯化的、可透析的人转移因子(简称dTFc),其作用在于刺激已下降了的非特异性皮肤反应性。本文报告3例严重的囊性痤疮并检查丁他们的细胞免疫功能。这些病人对常规治疗无效,其皮肤对常用抗原、结核菌素和念珠菌素的反应性明显下降。经用dTFc治疗后皮肤反应性增高,皮损减退。在淋巴细胞转化试验中,对植物血凝素的刺激,于治疗前后均在正常范围内;而对结核菌素(PPD)的反应则为阴性,治疗后也无明显的变化。dTFc的用法,最初一周皮下注射两次,然后14天注射两次,最后一月注射一次。
The authors have previously described a chromatography-purified, dialyzable human transfer factor (dTFc for short) that acts to stimulate a decreased non-specific skin reactivity. This article reports three cases of severe cystic acne and examines their cellular immune function. These patients are ineffective with conventional therapies, and their skin reactivity to commonly used antigens, tuberculin and candida is significantly reduced. After treatment with dTFc increased skin reactivity, decreased skin lesions. In the lymphocyte transformation test, the stimulation of phytohemagglutinin was within the normal range before and after treatment, while the reaction to tuberculin (PPD) was negative, with no significant change after treatment. dTFc usage, the first week of subcutaneous injection twice, then 14 days injections twice a month, the last injection.