硒化卡拉胶作为实验用药是我们利用天然硫酸酯多糖制备的硒化产物,已经制备的硒化卡拉胶含硒量可达2500—15000ppm。Kappa-硒化卡拉胶具有更为理想的生物可利用性和生理增益效果。 J.A.vinson报导亚硒酸钠对小鼠LD_(50)为12.7mg/kg,酵母硒对小鼠LD_(50)为37。mg/kg。本文报告Kappa-化卡拉胶对小鼠LD_(50)测定,Ames试验及其对叠氮钠致突变性抑制作 Selenized carrageenan, as an experimental drug, is a selenium product that we have made using natural sulfated polysaccharides. Selenized carrageenan selenium has been prepared with selenium content of 2500-15000 ppm. Kappa-selenated carrageenan has more desirable bioavailability and physiological gain effects. J.A.vinson reports that sodium selenite has a LD_ (50) of 12.7 mg / kg for mice and a yeast selenium has a LD_ (50) of 37 for mice. mg / kg. This article reports the Kappa-carrageenan LD_ (50) determination of mice, Ames test and its inhibition of sodium azide mutagenicity