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奥美拉唑（ｏｍｅｐｒａｚｏｌｅ，ＯＭＥ）为苯并咪唑类化合物，是一种新型胃酸分泌抑制剂，具有使胃壁细胞的质子泵（Ｈ＋，Ｋ＋ＡＴＰ酶系）受抑，从而起到抑制胃酸分泌的作用［１］，用于治疗反流性食管炎、胃泌素瘤、胃及十二指肠溃疡等［２］。ＯＭＥ现有剂型有片剂、
Omeprazole (OME), a benzimidazole compound, is a novel gastric acid secretion inhibitor which inhibits gastric acid secretion by inhibiting the proton pump (H +, K + -ATPase) of gastric parietal cells The role of [1], for the treatment of reflux esophagitis, gastrinoma, stomach and duodenal ulcer [2]. OME existing formulations of tablets,