尽管外科的发展和新抗生素的产生,手感染仍是一个严重的问题,因为它发病率高且可能致残。常常因为没有认识到污染手损伤的潜在严重性而延误了适当的治疗。延误和不适当的处理可引起高达50%的并发症。关于治疗手感染抗生素的选择,目前文献强调使用耐青霉素酶青霉素或头孢菌素。但比较这两种药物治疗手感染的效果及其和细菌学的关系的试验为数不多。为更合理地选择治疗手感染的抗生素,作者在Harborview医学中心对手感染进行了前瞻性、随机 Hand infections are a serious problem despite the development of surgery and the emergence of new antibiotics because of their high incidence and possible disability. Often, the proper treatment is delayed because the potential severity of contaminating hand injuries is not recognized. Delays and improper handling can cause up to 50% of complications. On the choice of treatment of hand infections with antibiotics, the current literature emphasizes the use of penicillin-resistant penicillins or cephalosporins. However, there are comparatively few trials comparing the efficacy of these two drugs in treating hand infections and their relationship to bacteriology. For a more rational treatment of hand-infected antibiotics, the authors conducted a prospective, randomized, randomized study at the Harborview Medical Center