本文介绍一种快速测定注射用防腐剂使用效果的方法。在针液中先加入各种不同浓度的防腐剂,再加测试菌种,经过0.5至6h,分别作菌落计数,测定溶液中残余活菌,间隔时间与细菌残余数据输入计算机,算出各种防腐剂对测试菌种降低10倍量需要的时间D 值与相关系数,如D 值≤2时则说明该防腐剂使用量符合英国药典的规定使用方法。 This article describes a rapid determination of the effect of injection of preservatives. Add various preservatives of different concentrations in the needles first, then add test strains, after 0.5 to 6h, count as colonies respectively, measure the remaining viable bacteria in the solution, the interval time and bacteria residual data into the computer to calculate a variety of anti-corrosion D agents to test strains to reduce the amount of time required D value and the correlation coefficient, such as D value ≤ 2, then the use of preservatives in line with the provisions of the British Pharmacopoeia usage.