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本研究旨在确定原因不明的慢性腹泻病人在结肠镜检查正常时其组织学异常的频率,以明确这些发现对临床治疗的意义,也为内镜医师决定是否应对外表正常的粘膜作活检提供实际可行的准则。作者对855例作结肠镜检查(595例)或可曲式直肠乙状结肠镜检查(260例)者中111例不明原因腹泻至少4~6周而对肠镜下肉眼观结肠粘模正常的活检标本进行了研究。接受结肠镜检查的76例病人中74例到达回盲部,70例进入回肠末端,2例到达肝曲。
The aim of this study was to determine the frequency of histological abnormalities in patients with chronic diarrhea of unknown origin under normal colonoscopy in order to clarify the significance of these findings for clinical treatment and to provide endoscopists the option of determining whether to respond to a biologically normal mucosal biopsy Feasible guidelines. The authors of colonoscopy in 855 cases (595 cases) or colorectal sigmoidoscopy (260 cases), 111 cases of unexplained diarrhea for at least 4 to 6 weeks under the colonoscopy colonoscopy normal biopsy specimens Were studied. Of the 76 patients who underwent colonoscopy, 74 reached the ileocecal part, 70 entered the distal ileum, and 2 reached the liver song.