论文部分内容阅读
目的:探明由不规则抗红细胞抗体而不是Rh-D抗体引起的新生儿溶血病的流行情况及发病率。设计:前瞻性队列研究。 方法:让总医院的所有儿科医生(n=380)和大学医院的接触人群(n=79)每月报告两年内(1996-1997)新生儿溶血病的临床病例。结果:答复率为97％。两年内共收到130例报告,其中49例不能肯定是RhD和AB30抗性。在有输血史(n=60)的群体中,29名孕妇(48％)在某一时间接受输血。在发现的抗体中,抗-c、抗-F和抗-K最常见。81例(包括三类未足月的婴儿)抗球蛋白试验阳性61例,阴性10例,由于早期子宫内输血,另有
Aims: To investigate the prevalence and incidence of neonatal hemolytic disease caused by irregular anti-red blood cell antibodies rather than Rh-D antibodies. Design: Prospective cohort study. Methods: All pediatricians in the general hospital (n = 380) and contact groups in university hospitals (n = 79) were reported monthly for clinical cases of hemolytic disease of newborns within two years (1996-1997). Results: The response rate was 97%. A total of 130 reports were received in two years, of which 49 were not surely resistant to RhD and AB30. In a population with a history of blood transfusions (n = 60), 29 pregnant women (48%) received transfusions at a time. Among the antibodies found, anti-c, anti-F and anti-K are the most common. 81 cases (including three types of under-infants) anti-globulin test was positive in 61 cases, negative in 10 cases due to early intrauterine transfusion, and another