冠状动脉造影的并发症少见且多为心血管本身的改变,本文报道1例造影后发生血管内溶血伴急性肾功能衰竭。患者,男,58岁,因劳力时胸骨后疼痛3年入院,无肾脏病和糖尿病既往史。血、尿常规,血小板,网织红细胞,血尿素及血清肌酐含量等均在正常范围。入院后以“泛影葡胺370”作心血管造影术,共用造影剂130ml,注射速度为12ml/sec。术后12小时,患者有(口恶)心,次晨出现黄疸伴严重少尿,仅排出黑色尿液10ml,镜检未见红细胞,但尿蛋白++,血红蛋白(?),尿胆素原(?),胆红素+;血尿素浓度从24mg%升至143mg%,血浆游离胆红素浓度从0.81mg%升至8mg%,血红蛋白浓度从14.2g/dl 降至12.8g/dl,网织红细胞升至3%,血浆中血红蛋白浓度升至0.26g/L(正常为0.01～0.04g/L)还原型结合珠蛋白浓度降至0.028g/L(正常为0.3～2.0g/L),血小板降 Complications of coronary angiography rare and mostly changes in the cardiovascular itself, this article reported in 1 case after angiography with intravascular hemolysis with acute renal failure. Patient, male, 58 years old, admitted to hospital for post-sternal pain due to labor, no previous history of kidney disease and diabetes. Blood, urine, platelets, reticulocytes, blood urea and serum creatinine levels are in the normal range. After admission to “meglumine meglumine 370” for cardiovascular angiography, sharing contrast agent 130ml, injection speed of 12ml / sec. 12 hours after the operation, the patient had (bad heart) heart, next jaundice with severe oliguria, excretion of black urine 10ml, microscopic examination without erythrocytes, but urinary protein ++, hemoglobin (?), Urobilinogen (?), Bilirubin +; blood urea concentration rose from 24mg% to 143mg%, plasma free bilirubin concentration increased from 0.81mg% to 8mg%, hemoglobin concentration decreased from 14.2g / dl to 12.8g / dl, Reticulocyte rose to 3%, plasma hemoglobin concentration rose to 0.26g / L (normal 0.01 ~ 0.04g / L) reducing haptoglobin concentration dropped to 0.028g / L (normal 0.3 ~ 2.0g / L) Thrombocytopenia