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[目的 ] 观察吲哒帕胺降压治疗对老年高血压合并血脂异常患者脂代谢的影响。 [方法 ] 选择 5 3例原发性高血压合并高脂血症的老年患者 ,随机分为 2组 ,分别接受吲哒帕胺 ( 2 5mgqd ,n =2 7)、卡托普利 ( 2 5mgbid ,n=2 6) 8周治疗。 [结果 ] 吲哒帕胺、卡托普利两组降压疗效相近 ,差异无统计学意义 (P >0 0 5 ) ,且均对血脂代谢无不良影响 (P >0 0 5 )。 [结论 ] 吲哒帕胺适宜用于老年高血压合并血脂异常患者的降压治疗。
[Objective] To observe the effect of indapamide antihypertensive therapy on lipid metabolism in elderly patients with hypertension and dyslipidemia. [Methods] A total of 53 elderly patients with essential hypertension complicated with hyperlipidemia were randomly divided into 2 groups and received 25 mg qd (n = 27) of indapamide and 25 mg bid , n = 2 6) 8 weeks treatment. [Results] Both indapamide and captopril had similar antihypertensive effects, with no significant difference (P> 0.05). All of them had no adverse effect on blood lipid metabolism (P> 0.05). [Conclusion] Indapamide is suitable for the antihypertensive treatment of elderly patients with hypertension and dyslipidemia.