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目的 :探讨进驻高原战士红细胞免疫功能改变的发生机制 ,为防治高原血液病和机体免疫系统疾病提供科学依据 ;方法 :对进驻高原不同时间、不同海拔地区的年轻战士463例运用免疫学等方法进行红细胞免疫功能检测 ;结果 :初进高原 2周～半年内RBC -C3b花环率免疫功能显著减低 (P <0 .0 1 ) ,RBC -IC花环率明显升高 (P <0 .0 1 )。随着时间的推移 ,3年后红细胞免疫功能逐渐恢复正常 ;结论 :急进高原地区战士半年内可引起红细胞免疫功能的改变。
OBJECTIVE: To explore the mechanism of erythrocyte immune function in high altitude soldiers and to provide scientific basis for the prevention and treatment of plateau hematological diseases and immune system diseases. Methods: 463 young soldiers who were stationed in the plateau at different times and at different altitudes were immunized Results: The rate of RBC-C3b rosette immunosuppression significantly decreased (P <0.01) and the rate of RBC-IC rosette increased significantly (P <0.01). With the passage of time, the immune function of erythrocytes gradually returned to normal after 3 years; Conclusion: The soldiers who hurried into the plateau can cause the change of erythrocyte immune function within 6 months.