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目的观察经鼻持续气道正压通气(NCPAP)治疗小儿重症肺炎的临床疗效。方法将54例小儿重症肺炎随机分为2组,对照组28例,在综合治疗基础上给予鼻导管吸氧治疗,治疗组26例,在综合治疗基础上应用NCPAP治疗,比较2组治疗前、后的临床表现、血气分析及并发症。结果采用NCPAP治疗24 h后,心率、呼吸、危重症评分、临床症状缓解时间及血气分析指标改善均较常规吸氧治疗组明显,差异均有统计学意义(P均<0.01);NCPAP治疗还能缩短患儿心率、呼吸恢复正常时间及肺部体征消失时间,并可减少心功能不全、消化道出血等并发症的发生,2组间的差异均有统计学意义(P均<0.05)。结论 NCPAP治疗小儿重症肺炎的临床疗效肯定,具有操作简便、无创、经济实用等优点,值得临床推广。
Objective To observe the clinical efficacy of nasal continuous positive airway pressure (NCPAP) in the treatment of severe pneumonia in children. Methods 54 cases of severe pneumonia in children were randomly divided into two groups, the control group of 28 cases, on the basis of comprehensive treatment of nasal catheter oxygen therapy, the treatment group of 26 patients on the basis of comprehensive treatment with NCPAP treatment, compared two groups before treatment, After the clinical manifestations, blood gas analysis and complications. Results After treatment with NCPAP for 24 hours, heart rate, respiration, critical illness scores, clinical symptom relief time and improvement of blood gas analysis indexes were significantly higher than those of conventional oxygen therapy group (all P <0.01); NCPAP treatment Can shorten the children’s heart rate, respiratory resuming normal time and the disappearance of the time of the lung signs, and can reduce the incidence of cardiac insufficiency, gastrointestinal bleeding and other complications, the difference between the two groups were statistically significant (P all <0.05). Conclusion The clinical efficacy of NCPAP in the treatment of pediatric severe pneumonia is definite. It has the advantages of simple operation, non-invasive, economical and practical, which is worthy of clinical promotion.