自体骨髓移植(ABMT)治疗急性白血病在国内外已引起广泛重视。然而,自体骨髓中残存的白血病细胞是ABMT后导致白血病复发的主要原因之一,因此,清除此类白血病细胞,即骨髓体外净化已成为目前ABMT的主要研究课题。我们自1988年以来,进行了微波对白血病细胞影响的实验研究,并应用微波净化的ABMT治疗急性白血病6例。现总结报告如下。 材料与方法 一,病例:一般情况见表1。ABMT前行全面查体,发现并清除隐性病灶。自预处理前3天起迁居层流病室(100级),严密隔离,直到周围血中性粒细胞恢复至0.5×10~9/L时为止。在隔离期进无菌饮食,口服肠道消毒剂(新霉素、复方新诺 Autologous bone marrow transplantation (ABMT) in the treatment of acute leukemia has attracted wide attention at home and abroad. However, residual leukemic cells in autologous bone marrow are one of the major causes of leukemia recurrence after ABMT. Therefore, purifying such leukemia cells, that is, ex vivo purification of bone marrow, has become the major research topic of ABMT. Since 1988, we conducted an experimental study of the effects of microwave on leukemic cells and applied microwave ablation of ABMT to treat 6 cases of acute leukemia. The report is summarized as follows. Materials and methods First, the case: the general situation in Table 1. ABMT comprehensive physical examination before, to find and remove hidden lesions. Three days before the pretreatment moved to laminar flow ward (100), and close the isolation until the peripheral blood neutrophils recovered to 0.5 × 10 ~ 9 / L when. Into a sterile diet in the isolation period, oral gut disinfectant (neomycin, cotrimoxazole