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目的了解南阳市中华按蚊对DDT、马拉硫磷、溴氰菊酯及氟氯氰菊酯4种杀虫剂的抗药性现状,为制定防治对策提供科学依据。方法采用WHO成蚊滤纸接触法,以区分剂量死亡率判定抗性程度。结果中华按蚊对溴氰菊酯、氟氯氰菊酯、马拉硫磷3种药物的区分剂量死亡率在80%～97%之间,为初步抗性群体。对DDT的区分剂量死亡率<80%,为抗性群体。结论 DDT停用多年后仍有较高的抗药性,而菊酯类药物的抗药性初步形成,其未来抗药性发展可能成为媒介按蚊控制的最大障碍,应加强抗药性监测,以便有效控制媒介按蚊。
Objective To understand the resistance status of Anopheles sinensis to DDT, malathion, deltamethrin and cyfluthrin insecticides in Nanyang and provide a scientific basis for the development of control strategies. Methods The WHO adult mosquito filter paper contact method was used to determine the degree of resistance by discriminating dose mortality. Results The discriminant dose mortality of Anopheles sinensis against deltamethrin, cyfluthrin and malathion was between 80% and 97%, which was the initial resistant population. DDT differentiated dose mortality <80%, for the resistant population. Conclusion Although DDT is still inactive for many years, the drug resistance of pyrethroids is initially formed. The future development of drug resistance may be the biggest obstacle to the control of Anopheles vectors. Drug resistance monitoring should be strengthened in order to effectively control the media Anopheles.