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目的：探讨红细胞生成素对慢性肾功能衰竭（肾衰）病人红细胞免疫功能的影响。方法：分别检测慢性肾衰病人和健康人的人红细胞Ｃ３ｂ受体花环率（ＲＣＲ）和红细胞免疫复合物花环率（ＲＩＣＲ）。结果：红细胞生成素治疗组慢性肾衰病人ＲＣＲ为９．２％±０．９％，高于非红细胞生成素治疗组２．６％±１．３％，低于健康人组１４．２９６±２．８％；前组肾衰病人ＲＩＣＲ为１１．２％±０．８％，低于后组１５．０％±１．５％，高于健康人组７．６％±１．１％。结论：慢性肾衰病人红细胞免疫功能低下，红细胞生成素治疗不仅增加红细胞数量，而且提高红细胞免疫功能。
Objective: To investigate the effect of erythropoietin on erythrocyte immune function in patients with chronic renal failure (renal failure). Methods: The RBC and RICR of erythrocyte C3b receptor were detected in patients with chronic renal failure and healthy people respectively. Results: The RCR of patients with chronic renal failure treated with erythropoietin was 9.2% ± 0.9%, higher than that of non-erythropoietin-treated patients (2.6% ± 1.3%) and lower than that of healthy subjects (14.296 ± 2.8%. The RICR of the former group was 11.2% ± 0.8%, lower than that of the latter group 15.0% ± 1.5%, higher than that of the healthy group 7.6% ± 1.1% . Conclusion: Erythrocyte immunocompromised patients with chronic renal failure, erythropoietin treatment not only increase the number of red blood cells, but also improve the immune function of red blood cells.