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目的:探讨康艾注射液联合化疗对胃肠道肿瘤患者免疫功能及生活质量的影响。方法:将112例胃肠道肿瘤患者随机分为2组各56例,对照组行常规化疗方案治疗,观察组在对照组的基础上加用康艾注射液治疗,比较2组临床疗效、毒副反应、治疗前后存活质量及免疫功能指标。结果:临床有效率观察组为64.29%,对照组为32.14%,2组比较,差异有统计学意义(P<0.05)。治疗后2组生活质量评分及CD3、CD4、CD8、CD4/CD8等指标均较治疗前明显改善(P<0.05),观察组各项指标改善均优于对照组(P<0.05)。不良反率为观察组为26.79%,对照组为89.29%,2组比较,差异有统计学意义(P<0.05)。结论:康艾注射液联合化疗能有效提高胃肠道肿瘤患者免疫功能,减少不良反应,提高患者生活质量。
Objective: To investigate the effect of Kangai injection combined with chemotherapy on immune function and quality of life in patients with gastrointestinal cancer. Methods: One hundred and twelve gastrointestinal cancer patients were randomly divided into two groups of 56 patients. The control group was treated with conventional chemotherapy. The observation group was treated with Kang Ai Injection on the basis of the control group. The clinical curative effect and toxicity Side effects, the quality of life before and after treatment and immune function. Results: The clinical effective rate was 64.29% in the observation group and 32.14% in the control group. There was significant difference between the two groups (P <0.05). The quality of life scores, CD3, CD4, CD8, CD4 / CD8 and other indexes in the two groups after treatment were significantly improved (P <0.05), and all the indexes in the observation group were better than those in the control group (P <0.05). Adverse reaction rate was 26.79% in the observation group and 89.29% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Kangai injection combined with chemotherapy can effectively improve the immune function of gastrointestinal cancer patients, reduce adverse reactions and improve the quality of life of patients.