论文部分内容阅读
目的:在睡眠脑电图引导下的Quisi快速检测法的建立,并探讨Quisi在老年失眠症诊断中的价值。方法:对64例老年失眠症患者和56名正常老年受试者同时做Quisi和睡眠脑电图(PSG)检测。并以日本SEEG-1518K为检测标准,与德国Quisi进行比较研究。同时做失匹性负波检测。结果:(1)在56名正常老年受试者中,除暂停、伪迹和第3、第4阶段4项睡眠参数Quisi和PSG两工具不能比较外,其他11项指标比较差异均无统计学意义(P>0.05)。(2)老年失眠症组与正常老年受试者Quisi比较,主要见:实际睡眠时间减少[分别为(350.1±29.5)分和(463.9±22.7)分,P<0.01],睡眠潜伏期长[分别为(34.6±18.9)分和(20.0±8.8)分,P<0.01],醒觉时间长[分别为(37.9±16.1)分和(17.2±6.6)分,P<0.01],睡眠效率低[分别为(87.5±8.1)分和(96.0±5.0)分,P<0.01],第一阶段睡眠百分比高[分别为(30.9±18.2)分和(9.2±1.7)分,P<0.01],第三、第四阶段睡眠百分比低[分别为(9.0±5.5)分和(17.1±4.8)分,P<0.01]。(2)与正常老人组相比,老年失眠症组MMN潜伏期延迟,波幅下降(P<0.01)。与此同时,P300也见同一趋势变化(P<0.05或0.01)。结论:(1)Quisi检测作用与PSG相似,在心理咨询、外出巡诊和家庭病床上有应用前途,运用Quisi技术评估老年失眠症患者的睡眠生理学异常,更为快速简便和客观科学。(2)MMN和P300两个指标在临床上作为睡眠脑电检测的一种补充手段。
Objective: To establish Quisi rapid detection method under the guidance of sleep EEG and to explore the value of Quisi in the diagnosis of senile insomnia. Methods: Quisi and sleep electrogastrogram (PSG) were performed simultaneously in 64 senile patients with insomnia and 56 normal elderly subjects. And with Japan SEEG-1518K as the testing standard, compared with Germany Quisi. At the same time do the negative negative detection. Results: (1) Among the 56 normal elderly subjects, no significant differences were found in the other 11 indicators except for the pauses, artifacts, and the Quisi and PSG tools for the 4 sleep parameters in stages 3 and 4 Significance (P> 0.05). (2) Comparison of Quisi in elderly insomnia with normal elderly subjects showed that the actual sleep time decreased (350.1 ± 29.5) and (463.9 ± 22.7) points, respectively, P <0.01, and prolonged sleep latency (34.6 ± 18.9) points and (20.0 ± 8.8) points respectively, P <0.01], long wake-up time (37.9 ± 16.1 and 17.2 ± 6.6 respectively, P <0.01) (87.5 ± 8.1) and (96.0 ± 5.0) points, respectively, P <0.01], and the percentage of sleep in the first stage was high (30.9 ± 18.2 and 9.2 ± 1.7, P <0.01, respectively) Third, the low percentage of sleep in the fourth stage [(9.0 ± 5.5) points and (17.1 ± 4.8) points, P <0.01]. (2) Compared with the normal control group, the latency of MMN in senile insomnia group was delayed and the amplitude was decreased (P <0.01). In the meantime, P300 also saw the same trend change (P <0.05 or 0.01). Conclusion: (1) Quisi test is similar to PSG and has potential application in psychological counseling, outpatient visits and family beds. Quisi technique is used to evaluate sleep physiology in elderly patients with insomnia, which is more rapid and simple and objective. (2) MMN and P300 two indicators clinically as a complementary measure of sleep EEG detection.