引言早在1910年,Schwarz 提出了“无酸即无溃疡”的名言,它对十二指肠溃疡来说,至今仍被认为是正确的。佐-埃二氏综合征患者中90%以上有高胃酸分泌。通常,抑制酸分泌,已成为治疗溃疡病的原则。抑制胃酸分泌药物有三个主要类型:即抗胆碱能药、组胺 H_2受体拈抗药和促胃液素受体拮抗药。其代表性药物分别为阿托品、甲氰咪胍和丙谷胺。 INTRODUCTION As early as 1910, Schwarz proposed the famous quote, “No acid or ulcer,” which is still considered correct for duodenal ulcers. More than 90% of patients with Zoe-Erzurum syndrome have high gastric acid secretion. In general, inhibition of acid secretion has become the principle for the treatment of ulcer disease. There are three main types of drugs that inhibit gastric acid secretion: anticholinergics, histamine H 2 receptor antagonists and gastrin receptor antagonists. The representative drugs are atropine, cimetidine and promethazine.