·对于非常可能实施PCI的急性冠脉综合征患者,普拉格雷治疗的效果较好,比如ST段抬高的心肌梗死患者,或者冠脉造影显示无ST段抬高的心肌梗死患者。·老年患者应避免使用,除非有高危因素。·低体重患者可选择低维持剂量,但还需要进一步证实。·无ST段抬高的心肌梗死患者急诊常规选择普拉格雷还为时尚早。·急性冠脉综合征患者初始治疗选择普拉格雷的疗效还不明确,但已在研究之中。·复杂选择性PCI之后常规使用普拉格雷是有临床需求的,但在有进一步的证据之前还不宜使用。 • Prasugrel is better for patients with acute coronary syndrome who are most likely to have PCI, such as patients with ST-elevation myocardial infarction or patients with myocardial infarction who have no ST-segment elevation coronary angiography. Elderly patients should be avoided unless there is a risk factor. Low-weight patients can choose low maintenance dose, but still need further confirmation. • It is too early to routinely select prasugrel in patients with ST-elevation MI. The initial treatment of acute coronary syndrome patients choose prasugrel efficacy is not clear, but it has been studied. • The routine use of prasugrel after complex and selective PCI is clinically needed, but should not be used until further evidence is available.