目前对神经病理性疼痛(neuropathic pain,NP)的中枢神经病理生理学改变及其机制尚不了解。近十年来,随着神经影像技术的发展,现代无创的脑成像技术对NP的有关发病机制的研究中取得了明显进展,进一步加深了对中枢神经系统在慢性疼痛信息处理过程的了解,本文综述了NP的脑功能影像学改变的研究进展及其临床意义。 At present, the pathophysiology of central neuropathic pain (NP) pathophysiology and its mechanism are not understood. In recent ten years, with the development of neuroimaging technology, modern noninvasive brain imaging has made significant progress in the study of the pathogenesis of NP, further deepening the understanding of the central nervous system in the process of chronic pain information processing. The research progress and clinical significance of NP functional brain imaging changes.