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本文研究在无电解质异常和临床心脏病的男性高血压患者中的无症状性心肌缺血(SMI)的发生率和时间节律性及其与室性心律失常(VA)的关系。方法入选研究对象包括年龄35～70岁(平均61岁)伴有静息心电图异常的男性高血压患者。包括:正在接受利尿剂治疗且已≥6个月,舒张压<12.6kPa;未接受利尿剂治疗,但有高血压史并且正在接受非利尿类抗高血压药物,舒张压≥90但<14kPa。因为多项危险因素干预试验提示,应用利尿剂的患者发生猝死的危险较大,故入选者停止利尿药治疗并口服补充电解质1个月。每日给予400mmol氯化钾和400mg氧化镁。为了避免药物对VA的影响,将正在接受抗心律失常药、β受体阻滞剂、茶碱、洋地
This article studies the incidence and time rhythms of asymptomatic myocardial ischemia (SMI) and its association with ventricular arrhythmias (VA) in hypertensive patients without electrolyte abnormalities and clinical heart disease. Methods Participants included male hypertensive patients aged 35-70 years (mean 61 years) with resting ECG abnormalities. Including: diuretics undergoing therapy for ≥6 months and diastolic blood pressure <12.6 kPa; patients not receiving diuretic therapy but having a history of hypertension and receiving nondiuretic antihypertensive medications with diastolic blood pressure ≥90 but <14 kPa. Because a number of risk factors intervention test prompted the use of diuretics in patients with a greater risk of sudden death, so the participants stopped diuretics and oral supplementation electrolyte 1 month. 400 mmol potassium chloride and 400 mg magnesium oxide were given daily. In order to avoid the impact of drugs on VA, will be receiving anti-arrhythmic drugs, β-blockers, theophylline,