评价静脉注入硝酸甘油对梗塞范围影响的随机试验心电图改变符合急性心肌梗塞(AMI)的患者(≤75岁、心率≥55bpm、收缩压≥95mmHg且无明显高血压)于发病后平均10小时:56例静脉注入硝酸甘油,平均速率90μg/min,使平均动脉压降低10％,维持48小时,随后改为经皮给药72小时;另48例给予安慰剂。AMI后3个月死亡率:发病后 <10小时开始硝酸甘油治疗亚组为14％,而发病后≥10小时开始硝酸甘油治疗亚组、发病 Randomized Trial to Evaluate the Effect of Intravenous Nitroglycerin on Infarct Size Electrocardiographic Changes Patients with acute myocardial infarction (AMI) (≤75 years of age, heart rate ≥55 bpm, systolic blood pressure ≥95 mmHg with no significant hypertension) average 10 hours after onset: 56 Example, intravenous nitroglycerin, the average rate of 90μg / min, the average arterial pressure decreased by 10% for 48 hours, then changed to transdermal 72 hours; the other 48 patients given placebo. Mortality after 3 months of AMI: Subgroup of nitroglycerin treatment was <14% after <10 hours of onset, and nitroglycerin treatment subgroups> 10 hours after onset