随着肿瘤治疗水平的提高,恶性肿瘤患者得以长期生存,伴发第二肿瘤的情况已不少见。但急性白血病与恶性肿瘤叠合的报道甚少。我院收治1例急性早幼粒细胞白血病(APL)合并膀胱癌患者,报告如下。患者,女,41岁。因月经量增多18天,牙龈出血伴乏力11天,皮肤瘀斑3天,于1997年8月21日入院。查体:中度贫血貌,牙龈渗血,躯干、四肢可见散在瘀斑;表浅淋巴结未触及,胸骨压痛,心、肺正常,肝、脾未及,肛门见外痔。外周血象:血红蛋白71g/L,红细胞2.61×10~(12)/L,白细胞2.8×10~9/L,血小板56×10~9/L,网织红细胞0.022,中性杆状核细胞0.04,中性分叶核 With the improvement of the level of cancer treatment, patients with malignant tumors can survive for a long time, and it is not uncommon to have a second tumor. However, there are few reports about the overlap between acute leukemia and malignant tumors. In our hospital, 1 patient with acute promyelocytic leukemia (APL) complicated with bladder cancer was treated as follows. Patient, female, 41 years old. Due to an increase in menstrual flow for 18 days, bleeding gums were associated with fatigue for 11 days and skin blemishes for 3 days. They were admitted to hospital on August 21, 1997. Physical examination: Moderate anaemia, gingival oozing, visible disfigurement of the trunk and extremities, superficial lymph node untouched, sternal tenderness, normal heart and lungs, liver and spleen, and external anus. Peripheral blood: hemoglobin 71 g/L, red blood cells 2.61×10 12/L, leukocytes 2.8×10 9/L, platelets 56×10 9/L, reticulocytes 0.022, neutral rod-shaped nucleus cells 0.04, Neutral nucleus