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本文报告77例各种腹水病人血清-腹水总蛋白浓度梯度(SATPG)和白蛋白浓度梯度(SAAG)的测定结果.35例肝硬化(LC)和14例原发性肝癌(PHC)病人SATPG、SAAG分别为4.75±1.11、1.69±0.45和4.83±1.20、1.74±0.67;而21例肝外恶性肿瘤(EHC)和5例结核性腹膜炎(TBP)病人分别为1.71±0.78、0.86±0.44和1.72±0.76、0.88±0.44.LC和PHC病人SATPG≥3.0、SAAG≥1.1的频数分别占91.4%、91.4%和92.8%、85.7%;而全部EHC和TBP病人仅1例SATPG>3.0,3例SAAG>1.1,其中2例手术证实有门脉受压.另有2例心衰病人梯度亦升高.表明SAAG和SATPG能敏感地反映出腹水病人有无门脉高压,但不能区分良恶性腹水.
This paper reports the results of determination of total aspartate total protein concentration (SATPG) and albumin concentration gradient (SAAG) in 77 patients with various ascites.Among the 35 patients with cirrhosis (LC) and 14 patients with primary hepatocellular carcinoma (PHC) SAAG were 4.75 ± 1.11,1.69 ± 0.45 and 4.83 ± 1.20,1.74 ± 0.67, respectively; while 21 cases of EHC and 5 cases of tuberculous peritonitis were 1.71 ± 0.78, 0.86 ± 0.44 and 1.72 ± 0.76,0.88 ± 0.44.The frequencies of SATPG≥3.0 and SAAG≥1.1 in LC and PHC patients were 91.4%, 91.4% and 92.8%, 85.7% respectively, while only 1 case of SATPG> 3.0 and 3 cases SAAG in all EHC and TBP patients > 1.1, of which 2 cases of portal vein compression surgery confirmed.Another two cases of heart failure patients also increased the gradient.It shows that SAAG and SATPG can be sensitive to reflect ascites patients with or without portal hypertension, but can not distinguish between benign and malignant ascites.