胸腺素(一种胸腺激素)在 NZB/NZW 小鼠身上可以垂建细胞免疫已得到证明,但胸腺对人类全身性红斑狼疮及其它自身免疫病的影响还没有研究过。本研究首次证明在活动性全身性红斑狼疮病人周围血液内淋巴细胞中的无效细胞(Null Cells,既没有 T细胞标记也没有 B 细胞标记的淋巴细胞)经体外胸腺素处理后显著下降,但对正常人、非活动性全身性红斑狼疮病人及风湿性关节炎病人的周围血液淋巴细胞中 T 淋巴细胞、 Thymosin, a thymic hormone, has been shown to elicit cellular immunity in NZB / NZW mice, but the effects of the thymus on human systemic lupus erythematosus and other autoimmune diseases have not been studied. This study, for the first time, demonstrated that Null Cells (neither T-cell nor B-cell-labeled lymphocytes) in the peripheral lymphocytes of patients with active systemic lupus erythematosus decreased significantly after thymosin treatment Normal, non-active systemic lupus erythematosus patients and rheumatoid arthritis patients with peripheral blood lymphocytes in T lymphocytes,