中西医结合药物疗法联合个性化健康管理社区干预高血压随机平行对照研究

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[目的]观察中西医结合药物疗法联合个性化健康管理治疗高血压疗效。[方法]使用随机平行对照方法,将110例住院及门诊患者按就诊顺序号抽签方法简单随机分为两组。对照组55例中西医结合治疗,血管紧张素转换酶抑制剂、钙拮抗剂、血管扩张剂、交感神经抑制荆、利尿剂等,单独用药或联合用药,二联或三联,同类降压药不联合使用;辨证分型:冲任失调,二仙汤(仙茅、当归、巴戟天、仙灵脾各9g,黄柏、知母各4.5g),阳虚加枸杞、菊花;瘀血阻滞,血府逐瘀汤(桃仁12g,红花、生地黄、川芎、当归、赤芍各10g,牛膝9g,枳壳、桔梗各6g,柴胡、甘草各3g),胸痛加青皮,脘腹疼痛加香附、乳香,肝胁胀痛加土鳖虫、郁金、大黄;肝阳上亢,天麻钩藤饮(天麻9g,钩藤12g,石决明18g,川牛膝12g,栀子、杜仲、桑寄生各10g,黄芩、益母草、朱茯神各9g);肝肾阴虚,杞菊地黄丸(枸杞、菊花各10g,熟地黄、山药各12g,酒萸肉10g,泽泻、牡丹皮各9g,茯苓6g);痰浊中阻,半夏白术天麻汤(半夏9g,蔓荆子、白术、茯苓、天麻和陈皮各6g,炙甘草3g,大枣3枚,生姜片2片),痰多加桂枝、泽泻,肝阳亢盛加钩藤、赭石;阴阳两虚,金匮肾气丸(地黄15g,茯苓、山药、泽泻、山茱萸、牛膝各12g,附子10g,车前子9g,牡丹皮6g,蜂蜜30g);按摩:合谷、曲池、太冲、内关、太溪等。治疗组55例个性化健康管理:①健康教育:定期举行讲座和交流会等,发放健康宣传手册、张贴海报,讲解高血压病因、症状、检查、诊断、治疗方法、治疗作用、不良反应、并发症;②监测随访:建立病历档案,定期询问病情、检测血压,记录每次检测结果,根据病情指导药,高龄或行动不便者上门服务;③饮食指导:低盐饮食,多食富含优质蛋白、高维生素、高钾和具有防治高血压的食物(菌类、食物的根茎、海藻类、新鲜蔬菜水果、豆制品等),忌食高脂肪食物、甜食、烟酒,如肌肉、羊肉、鸡皮、熏肉、猪肝等;(④运动指导:鼓励多做有氧运动;⑤用药指导:严格遵医嘱用药,不擅自增减;中西医结合治疗同对照组。连续治疗1个月为1疗程。观测临床症状、血压、健康管理评分、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效37例,有效14例,无效4例,总有效率92.73%。对照组显效25例,有效18例,无效12例,总有效率78.18%。治疗组疗效优于对照组(P<0.05)。健康管理评分两组均有改善(P<0.01),治疗组优于对照组(P<0.05)。[结论]中西医结合药物疗法联合个性化健康管理治疗高血压,疗效满意,无严重不良反应,值得推广。 [Objective] To observe the effect of integrated traditional Chinese and western medicine and personalized medicine on the treatment of hypertension. [Methods] Using randomized parallel control method, 110 inpatients and outpatients were randomly divided into two groups randomly according to the lot number sequence of visiting doctor. The control group of 55 cases of Integrative Medicine, angiotensin converting enzyme inhibitors, calcium antagonists, vasodilators, sympathetic inhibition Jing, diuretics, alone or in combination, two or three, similar antihypertensive drugs are not Joint use; dialectical type: Chong Ren to the disorder, Erxian Tang (Curculigo, Angelica, Morinda, Epimedium 9g, Treats, Anemarrhenal 4.5g), Yang plus wolfberry, chrysanthemum; , Xuefuzhuyu Decoction (peach kernel 12g, safflower, Rehmannia, Chuanxiong, Angelica, red peony root 10g, Achyranthes 9g, Citrus aurantium, Campanulaceae 6g, Bupleurum, licorice each 3g), chest pain plus blue skin, Ache, liver and bowel pain plus Eupolyphaga, turmeric, rhubarb; liver yang Kang, Tianma Goutengyin (Gastrodia 9g, Uncaria 12g, Cassia 18g, Achyranthes 12g, gardenia, Eucommia, Sang and parasitic 10g, Scutellaria, Motherwort, Zhu Fu Shen of the 9g); liver and kidney, Qi Ju Di Huang Wan (wolfberry, chrysanthemum each 10g, Rehmannia, yam 12g, Cornel 10g, Alisma, Each 9g, Poria 6g); phlegm obstruction, Pinellia Atractylodes Tianma Tang (Pinellia 9g, Vitex, Atractylodes, Poria, Gastrodia and Citrus 6g, Zhigancao 3g, jujube 3, 2 slices of ginger) , Add more Guiyang sputum, Yin and yang deficiency, Jingui Shenqi Wan (Rehmannia 15g, Poria, yam, Alisma, dogwood, Achyranthes each 12g, monkshood 10g, Plantago 9g, tree peony 6g , Honey 30g); massage: Hegu, Quchi, Taichong, Neiguan, too Creek and so on. 55 cases of treatment group personalized health management: ① health education: regular lectures and exchanges, etc., issue health brochures, posters, to explain the cause of hypertension, symptoms, examination, diagnosis, treatment, treatment, adverse reactions, complications Disease; ② monitoring follow-up: the establishment of medical records, regularly asked the disease, blood pressure, record each test results, according to the disease guidance drugs, elderly or people with limited mobility services; ③ diet guidance: low-salt diet, eat more high- High vitamins, high potassium and foods with high blood pressure (fungi, rhizomes of foods, seaweed, fresh fruits and vegetables, soy products, etc.), avoid high fat foods, sweets, tobacco and alcohol such as muscle, lamb, , Bacon, pig liver, etc .; (④ exercise guide: to encourage more aerobic exercise; ⑤ medication guidance: strict compliance with medical advice, not unauthorized increase or decrease; Integrative Medicine treatment with the control group. Continuous treatment for 1 month for a course of treatment The clinical symptoms, blood pressure, health management score and adverse reactions were observed.Results The treatment group was markedly effective in 37 cases, effective in 14 cases and ineffective in 4 cases, the total effective rate was 92.73%. The effective rate of the treatment group was better than that of the control group (P <0.05). The health management score was improved in both groups (P <0.01), and the treatment group was superior (P <0.05). [Conclusion] Integrative medicine therapy combined with personalized health management to treat hypertension, with satisfactory curative effect and no serious adverse reactions, is worth popularizing.
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