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目的探讨胃十二指肠疾病患者的生化变化规律。方法从胃肠激素、氧自由基和体液免疫等方面对患者进行同步观察。结果发现胃十二指肠患者胃泌素、胃动素和总羰基水平比正常人明显升高,IgG和IgM明显降低。并发现生长抑素与胰高血糖素之间呈负相关,IgG与IgA和IgM,IgA与IgM之间呈正相关。结论胃十二指肠疾病患者胃酸分泌增加,胃肠运动加快,体液免疫功能低下。
Objective To investigate the biochemical changes of patients with gastroduodenal diseases. Methods The patients were observed synchronously from gastrointestinal hormones, oxygen free radicals and humoral immunity. The results showed that patients with gastroduodenal gastrin, motilin and total carbonyl levels were significantly higher than normal, IgG and IgM was significantly lower. And found that somatostatin and glucagon was negatively correlated, IgG and IgA and IgM, IgA and IgM was positively correlated. Conclusions Patients with gastroduodenal diseases have increased gastric acid secretion, accelerated gastrointestinal motility and low humoral immune function.