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1979～1980年对64例晚期血吸虫病患者的免疫学检查包括植物血凝素皮试,淋巴细胞转化率,E-玫瑰花结,血清IgG、IgA、IgM、C_3、CH50及HBsAg(RPHA法)作了观察。结果免疫功能低下者有:(1)植物血凝素皮试54例(84.4％),(2)淋巴细胞转化率36例(56.2％),(3)E—玫瑰花结48例(75.0％),(4)C_3 35例(54.7％),CH50 29例(45.4％)。而IgG、IgA、IgM偏高,分别为42例(65.62％),19例(29.68％),33例(51.56％)。总的看来,晚期血吸虫病患者的细胞免疫功能低下者55例(85.93％),可见晚期血吸虫病患者的细胞免疫功能低下很显著。 HBsAg阳性者34例(53.12％)。就细胞免疫功能低下及HBsAg阳性率高的临床意义进行了探讨;
From 1979 to 1980, immunological examination of 64 patients with advanced schistosomiasis included phytohemagglutination test, lymphocyte transformation, E-rosette, serum IgG, IgA, IgM, C_3, CH50 and HBsAg (RPHA method) Made an observation. Results Immunocompromised patients were: (1) 54 cases (84.4%) with leprosy skin test, (2) 36 cases with lymphocyte transformation rate (56.2%), (3) 48 cases with 75% ), (4) 35 cases of C_3 (54.7%) and 29 cases of CH50 (45.4%). IgG, IgA and IgM were higher in 42 cases (65.62%), 19 cases (29.68%) and 33 cases (51.56%). In general, 55 cases (85.93%) of patients with advanced schistosomiasis have low cellular immunity, showing that the cellular immune function of patients with advanced schistosomiasis is very low. 34 cases were HBsAg positive (53.12%). The clinical significance of low cellular immune function and high HBsAg positive rate was discussed.