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目的 探讨低级脑星形细胞瘤的预后因素。方法 回顾1986～1993年经手术病理证实为Ⅰ级星形细胞瘤的69个病例,采用COX模型分析有关预后因素与生存期之间的关系。结果 表明年龄、手术前后神经机能状态、手术切除肿瘤的程度、手术后放射治疗等因素与病人的生存密切相关。结论 对低级脑星形细胞瘤的患者(尤其是青壮年者),应在尽量保存神经功能的前提下,最大限度的切除肿瘤,争取做到肿瘤的全切除、次全切除,手术后辅以放射疗法等。以提高病人的长期生存率。
Objective To investigate the prognostic factors of low grade astrocytoma. Methods A retrospective review of 69 cases of grade Ⅰ astrocytoma confirmed by surgery and pathology from 1986 to 1993 was performed. COX model was used to analyze the relationship between prognostic factors and survival. The results showed that age, preoperative and postoperative neurological status, degree of surgical resection of the tumor, postoperative radiotherapy and other factors are closely related to the patient’s survival. Conclusion Low-grade astrocytoma patients (especially young adults) should try to save the nerve function of the premise, the maximum tumor removal, so as to achieve the tumor total excision, subtotal resection, after surgery supplemented by Radiation therapy. To improve the patient’s long-term survival.