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聚合物已广泛用于医药领域,如人造器官、医用粘合剂、高分子药物、医用制品等,还可以用作药物辅料,如崩解剂、赋形剂、包衣剂等,该领域一个较为鲜知的应用——药物固化已开始被人们注意并广泛应用。一、固化及药物固化的概念聚合物单体在辐射等条件的作用下相互交联固定成型称为聚合体,这一过程叫做固化(immobilization)。如将药物与聚合物单体混合进行固化,可将药物包埋或连接在聚合物中,形成释药系统(Drug Delivery System)。在体内缓慢持续地释放药物,达到治疗目的。这种给药系统具有以下特点:1.较高的
Polymers have been widely used in the field of medicine, such as artificial organs, medical adhesives, polymer drugs, medical products, etc., and also can be used as pharmaceutical excipients such as disintegrants, excipients, coating agents and the like More rarely known applications - drug curing has begun to be noted and widely used. First, the concept of curing and curing drugs Polymer monomers under the influence of radiation and other conditions cross-linked fixed shape called polymer, the process is called immobilization (immobilization). If the drug is mixed with the polymer monomer for curing, the drug may be embedded or attached to the polymer to form a Drug Delivery System. Slowly and continuously release the drug in the body for therapeutic purposes. This delivery system has the following characteristics: 1. Higher