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目的探讨二重血浆分离联合早期肠内营养治疗高脂血症性胰腺炎的临床疗效。方法将29例急性高脂性胰腺炎患者分为实验组和对照组,两组均予以常规治疗及二重血浆分离,实验组给予早期肠内营养,观察两组治疗前后血脂及血浆内毒素变化情况。结果两组患者经二重血浆分离后血清甘油三酯及血清胆固醇均下降。治疗后第3、7天血浆内毒素水平实验组分别为(50.33±8.61)EU/L、(27.46±8.83)EU/L,对照组分别为(63.35±9.24)EU/L、(50.24±9.02)EU/L。结论二重血浆分离联合早期肠内营养治疗高脂血症性胰腺炎能降低血脂并保护肠道粘膜屏障。
Objective To investigate the clinical efficacy of dual plasma combined with early enteral nutrition in the treatment of hyperlipidemic pancreatitis. Methods Twenty-nine patients with acute hyperlipidemic pancreatitis were divided into experimental group and control group. Both groups were given routine treatment and double plasma separation. The experimental group was given early enteral nutrition. The changes of blood lipids and plasma endotoxin before and after treatment were observed . Results Serum triglyceride and serum cholesterol were decreased in both groups after double plasma separation. The levels of plasma endotoxin in the experimental group on the 3rd and 7th day after treatment were (EU) 50.33 ± 8.61 / (27.46 ± 8.83) EU / L and control group 63.35 ± 9.24 EU / L 50.24 ± 9.02 ) EU / L. Conclusions Dual plasma combined with early enteral nutrition for hyperlipidemic pancreatitis can reduce blood lipid and protect the intestinal mucosal barrier.