高血压,急性心肌梗塞(AMI)患者常因用排钾利尿剂后有出现低钾血症的危险,故研究低钾血症的发生、病理及后果是十分重要的课题。正常体内98%的钾贮存于细胞内(细胞内钾150mmol/L,细胞外钾3.5～5.3mmol/L),当钾丢失200～400mmol时,可能出现缺钾症状。但钾丢失数百mmo1后,只要细胞内钾浓度不改变,仍不引起症状,这说明细胞外钾丢失更为重要。此种关系可由Nernst Hypertension, acute myocardial infarction (AMI) patients often due to the risk of hypokalemia after using potassium row diuretics, so the study of hypokalemia, pathology and consequences is a very important issue. 98% of normal potassium stored in cells (intracellular potassium 150mmol / L, extracellular potassium 3.5 ~ 5.3mmol / L), potassium loss of 200 ~ 400mmol, potassium deficiency symptoms may occur. However, potassium lost hundreds of mmo1, as long as the intracellular potassium concentration does not change, still does not cause symptoms, indicating extracellular potassium loss is even more important. This relationship is available from Nernst