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目的研究2006-2010年乌鲁木齐市围产儿的出生缺陷资料,分析乌鲁木齐市主要出生缺陷发生类型、影响因素及变化规律,并提出干预措施。方法采用流行病学回顾性调查研究方法,收集2006～2010年乌鲁木齐市6家主要助产医院住院分娩的围产儿资料,数据采用SPSS 13.0软件建库并进行统计学描述及相关分析。结果 2006～2010年,乌鲁木齐市累计报告出生缺陷儿688例,出生缺陷总发生率为96.79/万,其中城市为110.5/万,农村为63.3/万,男性为98.07/万,女性为91.89/万。主要缺陷类型为总唇裂、多指(趾)、马蹄内翻足、肢体短缩、先天性脑积水。产妇年龄超过35岁,出生缺陷发生率最高。结论乌鲁木齐市出生缺陷发生率呈逐年上升趋势,并因城乡、性别、产妇年龄不同而有差异。出生缺陷产前诊断总体水平较落后。
Objective To study the birth defects data of perinatal infants in Urumqi from 2006 to 2010, analyze the types, influential factors and changes of the major birth defects in Urumqi, and put forward the intervention measures. Methods The epidemiological retrospective research methods were used to collect perinatal data from 6 major midwifery hospitals in Urumqi from 2006 to 2010. The data were collected by SPSS 13.0 software and analyzed statistically. Results From 2006 to 2010, a total of 688 birth defects were reported in Urumqi. The total incidence of birth defects was 96.79 / million, of which 110.5 in urban areas, 63.3 / rural in rural areas, 98.07 / million in men and 91.89 / . The main types of defects are total cleft lip, multiple fingers (toes), clubfoot, limb shortening, congenital hydrocephalus. Maternal age over 35 years old, the highest incidence of birth defects. Conclusions The incidence of birth defects in Urumqi is increasing year by year, and varies according to the age of urban and rural areas, gender and maternal age. Prenatal diagnosis of birth defects overall level of backward.