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本文用１２种抗体对２５例恶性纤维组织细胞瘤（ＭＦＨ）作免疫组化标记。结果３种ＭＦＨ细胞ＰＣＮＡ，Ｖｉ－ｍｅｎｔｉｎ均阳性。组织细胞样ＭＦＨ细胞和少数纤维母细胞样ＭＦＨ细胞并呈ＣＤ６８（Ｋｐ－１和ＰＧ－Ｍ１）阳性。除３例外，ＭＦＨ细胞对肌源性标记，神经源性标记和上皮性标记均阴性。破骨细胞样巨细胞ＰＣＮＡ阴性，ＣＤ６８阳性。多顿氏巨细胞ＰＣＮＡ阴性，ＣＤ６８、Ｍａｃ３８７、ｌｙｓｏｚｙｍｅ、α－ＡＴ呈不同程度阳性。说明ＭＦＨ是原始间叶细胞起源的肉瘤，可以向组织细胞、纤维母细胞双向分化。ＭＦＨ细胞是有高度增殖活性的肿瘤成分，而破骨细胞样巨细胞、多顿氏巨细胞则为缺乏增殖能力的临终细胞。
In this paper, 25 kinds of malignant fibrous histiocytoma (MFH) were immunohistochemically labeled with 12 kinds of antibodies. Results The three kinds of MFH cells were positive for PCNA and Vi-mentin. Tissue-like MFH cells and a few fibroblast-like MFH cells were stained positive for CD68 (Kp-1 and PG-M1). With 3 exceptions, MFH cells were negative for myogenic markers, neurogenic markers and epithelial markers. Osteoclast-like giant cells PCNA negative, CD68 positive. Dodosteen giant cell PCNA negative, CD68, Mac387, lysozyme, α-AT were positive to varying degrees. Description MFH is the original mesenchyme sarcoma origin, to tissue cells, fibroblasts two-way differentiation. MFH cells are highly proliferative tumor components, while osteoclast-like giant cells, Dodosteen giant cells are the lack of proliferation of terminal cells.