1969年Ashbaugh应用呼气末正压机械通气支持疗法(简称PFEP)治疗21例外科成人呼吸窘迫综合征(ARDS),取得了较好的疗效,当时被认为是ARDS治疗的一个重要突破。随着对ARDS病理生理的深刻认识和机械呼吸治疗技术的进步,对ARDS的治疗也不断提高。治疗ARDS的最终目标是缓解 In 1969, Ashbaugh treated 21 cases of surgical adult respiratory distress syndrome (ARDS) with positive end-expiratory mechanical ventilation support (PFEP) and achieved good results. At that time, it was considered as an important breakthrough in the treatment of ARDS. With the profound understanding of the pathophysiology of ARDS and advances in mechanical respiratory therapy, the treatment of ARDS has also been continuously improved. The ultimate goal of treating ARDS is to alleviate it