论文部分内容阅读
目的 前瞻性调查肝硬化患者的亚临床肝性脑病 (SHE)的发病情况。方法 35 6例正常对照和 175例无临床肝性脑病的肝硬化连续病例行数字连接试验 (NCT)和数字符号试验 (SDT) ,以对照组相应年龄段的 x± 2s为标准确定有无SHE。 结果 肝硬化中单独NCT或SDT异常分别是 34例(19.4% )和 16例 (9.1% ) ,二者均异常有 5 0例 (2 8.6 % ) ,合计有 10 0例 (5 7.1% )诊断为SHE。按Child Pugh分级 ,SHE分别是A级 46 .8%、B级 5 3.0 %和C级 76 .6 %。肝硬化病因和年龄对SHE检出率无显著影响。结论 无脑病症状的肝硬化中约 5 7.1%有SHE ,发病与肝功能受损程度有关
Objective To prospectively investigate the incidence of subclinical hepatic encephalopathy (SHE) in cirrhotic patients. Methods 35 cases of normal controls and 175 cases of clinical cirrhosis without clinical hepatic encephalopathy were studied by digital connection test (NCT) and digital sign test (SDT), and the control group with x ± 2s as the standard to determine the presence or absence of SHE . Results The abnormalities of NCT or SDT in cirrhosis were 34 (19.4%) and 16 (9.1%) respectively, both of which were abnormal (50.6%), with a total of 100 (5.11%) diagnoses For SHE. Classified by Child Pugh, SHE was 46.8% for Class A, 3.0% for Class B and 76.6% for Class C. The etiology and age of cirrhosis had no significant effect on the detection rate of SHE. Conclusions About 51.7% of patients with cirrhosis without encephalopathy have SHE. The incidence is related to the degree of impaired liver function