给家兔肼 １７．４和 ４１． ７ ｍｇ／ ｋｇ皮肤染毒，血中肼浓度的经时变化符合一级吸收一室模型；静注肼 ７．０ｍｇ／ｋｇ呈。室模型。肼皮肤染毒后能迅速透过家兔皮肤被吸收入血，几乎无吸收时滞，经 ０．７２～ １．８９ ｈ吸收相即基本结束，吸收率为 ６３％左右。静注肼在家兔体内分布极快，不到 ６ ｍｉｎ两室间分布已基本达动态平衡；肼在家兔体内是周身分布，周室稍“富集”。肼各途径染毒从家兔体内消除均较快，生物半衰期为１．４９～３．８０ ｈ，物质蓄积性弱，并且存在肾外消除途径。 Give rabbits hydrazine 17.4 and 41. 7 mg / kg skin exposure, the change of blood hydrazine concentration in time consistent with the first-order absorption model; intravenous hydrazine 7.0mg / kg were. Room model. Hydrazine hydrate skin can be quickly absorbed through the skin of rabbits into the blood, almost no absorption delay, the absorption phase after 0.72 ~ 1.89 h that is basically the end of the absorption rate of about 63%. Intravenous hydrazine distribution in rabbits extremely fast, less than 6 min distribution of the two rooms has reached a basic dynamic balance; hydrazine in the body of the rabbit is the whole body distribution, the peripheral ventricular a little “enriched.” Hydrazine all the way to get rid of the body from rabbits are faster, the biological half-life of 1.49 ~ 3.80 h, material accumulation is weak, and there are ways to eliminate outside the kidney.