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鼻息肉发病机理至今尚未明了。本文通过测定鼻息肉患者血液和鼻息肉组织离心上清液体的几项免疫学参数和鼻息肉的组织学改变, 来探讨变态反应在鼻息肉发病机理中的作用。IgE是Ⅰ型变态反应的介导抗体,鼻粘膜有合成IgE的能力。鼻部变态反应发生时此种能力显著增加,导致局部IgE增高。本组有22例(58％)鼻息肉IgE水平显著高于血清(P<
The pathogenesis of nasal polyps has not yet been clarified. In this paper, by measuring the immunological parameters of the supernatant fluid in the blood and nasal polyps of patients with nasal polyps and histological changes of nasal polyps to explore the role of allergies in the pathogenesis of nasal polyps. IgE is a type I allergic mediator, nasal mucosa with the ability to synthesize IgE. This ability to significantly increase when nasal allergy occurs results in increased local IgE. In this group, 22 cases (58%) of nasal polyps IgE levels were significantly higher than serum (P <