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目的 探讨职业、环境因素、某些药物、社会经济及生活行为因素与淋巴瘤发病的相关性。方法 采用 1∶2配对病例对照研究 ,恶性淋巴瘤 150例 (病例组 ) ,非肿瘤病例 3 0 0例 (对照组 ) ,结果用logistic回归分析。结果 ( 1)接触有机溶剂 ,如苯 [调整OR(aOR) =2 .78,P =0 .0 0 1]、香蕉水 (aOR =2 .2 8,P =0 .0 43 )、油漆 (aOR =1.96,P =0 .0 2 3 )和接触农药 ,包括有机磷类 (aOR =1.98,P =0 .0 3 4 )、菊酯类 (aOR =2 .57,P =0 .0 13 )以及有机氮类 (aOR =2 .55,P =0 .0 0 3 )会增加淋巴瘤发病的危险性。 ( 2 )经常使用一些药物 ,如阿斯匹林 (aOR =2 .3 6,P =0 .0 0 5)会使淋巴瘤发病的危险性增加。 ( 3 )饲养宠物狗 (aOR =1.76,P =0 .0 3 4 )与淋巴瘤发病的危险性增加有一定关系。 ( 4 )定期接受小剂量X线照射 (aOR =0 .49,P =0 .0 15)、经常患感冒 (aOR =0 .67,P =0 .0 2 4)则可能降低淋巴瘤发病的危险性。 ( 5)职业 (P >0 .0 5)、吸烟 (OR =1.0 1,P =0 .897)、戒烟 (OR =1.17,P =0 .0 73 )、饮酒 (aOR =1.2 6,P =0 .414 )、染发 (OR =1.0 6,P =0 .850 )、烫发 (OR =1.2 6,P =0 .43 8)、经济状况(OR =1.0 0 ,P =1.0 0 0 )和内向性格 (OR =1.2 6,P =0 .2 66)与淋巴瘤发病无明显相关性。结论 接触有?
Objective To explore the correlation between occupational and environmental factors, some drugs, socioeconomic and life behavior factors and the incidence of lymphoma. Methods A case-control study of 1: 2 was performed. 150 cases of malignant lymphoma (case group) and 300 cases of non-tumor cases (control group) were analyzed by logistic regression. Results (1) Exposure to organic solvents such as benzene [adjusted OR (aOR) = 2.78, P = .0 0 1], banana water (aOR = 2.2 8, aOR = 1.96, P = 0.023) and contact pesticides, including organophosphates (aOR = 1.98, P = 0.0334), pyrethroids (aOR = 2.57, P = 0.013 ) And organic nitrogen (aOR = 2.55, P = 0.003) increased the risk of lymphoma. (2) frequent use of some drugs, such as aspirin (aOR = 2.36, P = 0.050) will increase the risk of lymphoma. (3) Pet dogs raised (aOR = 1.76, P = 0.0304) had some relationship with the increased risk of lymphoma. (4) Regular low-dose X-ray irradiation (aOR = 0.49, P = 0.015) and frequent cold (aOR = 0.67, P = 0.024) may reduce the incidence of lymphoma Dangerous. (OR = 1.01, P = 0.987), smoking cessation (OR = 1.17, P = 0.073), alcohol consumption (aOR = 1.2 6, P = (OR = 1.06, P = 0.800), permedipulation (OR = 1.2 6, P = 0.43 8), economic status (OR = 1.0 0, P = 1.0 0 0) Personality (OR = 1.2 6, P = 0.266) had no significant correlation with the onset of lymphoma. Conclusion of contact?