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本文对160例缺血性心脑血管疾病患者的甲襞微循环(19项参数)和血液流变学(11项参数)进行了研究。结果显示:66.9％的患者甲襞微循环总积分异常,88.6％的患者血液流变学JB值异常。JB值与流态积分值和总积分值呈正性相关(P均<0.001,r分别为0.37和0.34),与襻周状态积分值相关性差(P<0.001,r=0.27),与形态积分值无相关性(P>0.05)。进一步分组研究显示:JB值正常组(31例)中,总积分值正常者占54.8％;JB值异常组(129例)中,总积分值异常者占72.1％;总积分值正常组(53例)中,JB值正常者占32.1％;总积分值异常组(107例)中,JB值异常者占86.9％。结果说明,大部分缺血性心脑血管疾病患者有微循环障碍和高粘滞血症,甲襞微循环与血液流变学改变之间存在正性相关,但并非完全相关。提示临床对缺血性疾病最好两项检查同时进行,并结合患者其它临床资料综合分析,提高临床诊断准确率。
In this paper, 160 cases of ischemic cardiovascular and cerebrovascular disease in patients with nailfold microcirculation (19 parameters) and hemorheology (11 parameters) were studied. The results showed that: 66.9% of patients with abnormal total nail fold microcirculation, 88.6% of patients with abnormal blood rheology JB value. JB value was positively correlated with the integral value of flow state and the total integral value (P <0.001, r = 0.37 and 0.34, respectively), and had no significant correlation with the integral state value (P <0.001, r = 0.27) No correlation (P> 0.05). Further grouping studies showed that in the normal JB group (31 cases), the total score was 54.8%; in the JB abnormal group (129 cases), the total score was abnormal (72.1%); the total score was normal Cases), the normal JB value accounted for 32.1%; total score abnormal group (107 cases), JB value of abnormal accounted for 86.9%. The results showed that most patients with ischemic cardiovascular and cerebrovascular disease have microcirculation and hyperviscosity. There is a positive correlation between microcirculation and changes of hemorheology, but not completely. Prompt clinical ischemic disease best two tests at the same time, combined with other clinical data of patients with a comprehensive analysis to improve the accuracy of clinical diagnosis.