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[目的]观察逐瘀降浊汤联合阿托伐他汀治疗脑梗塞疗效。[方法]使用随机平行对照方法,将94例住院患者按抛硬币法简单随机分为两组。常规改善脑组织微循环、降低颅内压力及抗血小板聚集治疗。对照组47例阿托伐他汀,20mg/次,睡前口服。治疗组47例逐瘀降浊汤(白术10g,甘草5g,黄连6g,山楂12g,茯苓15g,枳壳、红花各10g,三七6g,丹参、法半夏各10g),1剂/d,水煎200m L,早晚口服;阿托伐他汀治疗同对照组。连续治疗14d为1疗程。观测临床症状、胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL-L)、低密度脂蛋白(LDL-C)、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组痊愈11例,显效29例,有效6例,无效1例,总有效率97.87%。对照组痊愈2例,显效24例,有效15例,无效6例,总有效率87.23%。治疗组疗效优于对照组(P<0.05)。血脂两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]逐瘀降浊汤联合阿托伐他汀治疗脑梗塞疗效满意,无副作用,值得推广。
[Objective] To observe the curative effect of Zhuyu Jiangzhuo Decoction combined with atorvastatin on cerebral infarction. [Methods] Using randomized parallel control method, 94 inpatients were randomly divided into two groups according to the coin-tossing method. Conventional improve brain tissue microcirculation, reduce intracranial pressure and anti-platelet aggregation therapy. Control group, 47 cases of atorvastatin, 20mg / times, oral before going to bed. The treatment group, 47 cases of Zhuyu Jiangzhuo soup (Atractylodes 10g, licorice 5g, Coptis 6g, hawthorn 12g, Poria 15g, Citrus aurantium, saffron 10g, 376g, Salvia, Pinellia each 10g), 1 / , Decoction 200m L, morning and evening oral; atorvastatin treatment with the control group. Continuous treatment 14d for a course of treatment. The clinical symptoms, cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-L), low density lipoprotein (LDL-C) and adverse reactions were observed. Continuous treatment of 3 courses to determine the efficacy. [Results] The treatment group recovered in 11 cases, markedly effective in 29 cases, effective in 6 cases, ineffective in 1 case, the total effective rate was 97.87%. The control group cured 2 cases, effective in 24 cases, effective in 15 cases, 6 cases, the total effective rate was 87.23%. The treatment group was better than the control group (P <0.05). Blood lipids were improved in both groups (P <0.05), the treatment group improved better than the control group (P <0.05). [Conclusion] Zhuyu Jiangzhuo Decoction combined with atorvastatin is effective in treating cerebral infarction without side effects and is worth promoting.