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将我院４１８例手术吻合切除肝癌病例分为近１０年组（１７５例）和前２５年组（２４３例），并进行了对照分析。近１０年组的主要特点是：（１）体检发现的亚临床肝癌较前２５年组多（分别为２６．３％，５．３％，Ｐ＜０．０１）；（２）临床Ⅰ期病例较前２５年组多（２６．３％，１．６％，Ｐ＜０．０１）；（３）手术切除病例较前２５年组高（５６．１％，４０．４％，Ｐ＜０．０１）；（４）手术死亡率较前２５年组低（１．７％，８．６％，Ｐ＜０．０１）；（５）局部切除较前２５年组多（３６．０％，０．２％，Ｐ＜０．０１）；（６）复发癌再治疗是近１０年组独有的；（７）术后１，３，５年生存率较前２５年组高（８０．６％，４７．３％，３４．９％，５７．２％，３０．６％，２５．２％，Ｐ＜０．０１）。本文资料说明原发性肝癌诊治方法的变迁表现了肝癌早期治疗水平的提高，反映了肝癌基础和临床研究的进步。
The 418 surgically resected liver cancer cases in our hospital were divided into nearly 10-year group (175 cases) and the first 25 years group (243 cases), and a control analysis was performed. The main features of the group in the past 10 years are: (1) The number of subclinical liver cancers found on physical examination was higher than the previous 25-year group (26.3%, 5.3%, P<0.01); (2) Clinical Phase I The number of cases was more than that of the previous 25 years (26.3%, 1.6%, P<0.01); (3) The cases of surgical resection were higher than those in the previous 25 years (56.1%, 40.4%, P< 0.01); (4) The operative mortality was lower than that of the previous 25-year group (1.7%, 8.6%, P<0.01); (5) The local resection was more than the previous 25-year group (36.0) %, 0.2%, P <0.01); (6) Retreatment of recurrent cancer was unique in the 10-year group; (7) The 1-, 3-, and 5-year survival rates were higher than those in the previous 25-year group ( 80.6%, 47.3%, 34.9%, 57.2%, 30.6%, 25.2%, P<0.01). This article shows that the changes in the diagnosis and treatment of primary liver cancer show the improvement of the early treatment of liver cancer, reflecting the progress of basic and clinical research of liver cancer.