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作者于1989年6月至1991年3月用麻疹减毒活疫苗治疗63例小儿哮喘,获近期控制23例,显效19例,有效14例,无效7例,总有效率为88.88%。临床分型有效率:外源型75%,内源型100%,混合型90.9%,各型间疗效有显著性差异(P<0.05)。于治疗前后检测外周血CD_3~+细胞、CD_4~+细胞、CD_8~+细胞及Ts抑制活性,结果显示治疗前后各项免疫指标无变化,提示麻苗治疗效应与T淋巴细胞亚群的数量和抑制性细胞的功能无关,其作用机制有待有一步研究。
In June 1989 to March 1991 with live attenuated measles vaccine treatment of 63 cases of pediatric asthma, 23 were recently controlled, effective in 19 cases, effective in 14 cases, 7 cases, the total effective rate was 88.88%. Clinical classification efficiency: 75% exogenous, 100% endogenous, mixed 90.9%, the efficacy of each type was significantly different (P <0.05). Before and after treatment, the detection of peripheral blood CD_3 ~ + cells, CD_4 ~ + cells, CD_8 ~ + cells and Ts inhibition activity showed no change before and after the treatment of various immune indicators, suggesting that Miao treatment effect and T lymphocyte subsets and Inhibitory cell function has nothing to do, its mechanism needs further study.