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恶性肿瘤的基因治疗是近年来倍受重视的研究课题之一。Ram等报道[1],采用基因重组技术,将单纯疱疾病毒(herpessimplexvirus,HSV)的胸苷激酶(thyAndinekinase,TK)基因克隆至逆转录病毒表达载体,辅以环氧鸟苷(ganciclovir,GCV)治疗神经胶质瘤,收到良好效果.这种以T
Gene therapy of malignant tumors is one of the most important research topics in recent years. Ram et al. [1] reported that the gene of thyAndinekinase (TK) of herpes simplex virus (HSV) was cloned into a retroviral vector by gene recombination and supplemented with ganciclovir (GCV ) Treatment of glioma, received good results. This to T