目的观察长托宁联合利多卡因在宫腔镜检查中的临床效果。方法案例分析法和比较分析法。选择我院门诊需进行宫腔镜检查的患者200例,随机分成两组：①观察组100例,宫腔镜检查前30min肌肉注射长托宁0.5mg,检查时宫颈注射1%利多卡因2ml；②对照组100例,单纯于宫腔镜检查时宫颈注射1%利多卡因2ml。比较两组用药后的临床效果。观察检查中患者的血压、心率、血氧饱和度、宫劲口松弛度、疼痛程度及术后不良反应。结果两组在血压、心率、血氧度饱和并发症方面比较,无明显变化,差异无统计学意义(﹥0.05)；在宫颈口松弛度和疼痛及检查后不良反应方面显著优于对照组,两者的差异有统计学意义(0.05).The cervical relaxation in observation group was bet er and the pain and postoperative side ef ects in observation group were less than that of the control group.There was a statistical y significant dif erence between the groups ( <0.05).Conclusion The penehyclidine hydrochloride combined with lignocaine can reduce the risk and improve the safety of diagnostic hysteroscopy,can help relax the cervical tense,release pain and reduce the rate of nausea and vomiting or other complications.So it can be easily accepted by the patients and can make the examination more successful.