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目的评价非侵入性试验在肺癌诊断中的价值。方法采用胸片、胸部计算机断层摄影（ＣＴ），血清癌胚抗原（ＣＥＡ），β２－微球蛋白（β２－Ｍ），铁蛋白（ＳＦ），唾液酸（ＳＡ）同步检测肺癌３６例，肺良性病变（ＢＰＤ）３０例。结果ＣＥＡ，β２－Ｍ，ＳＦ，ＳＡ水平，肺癌组明显高于ＢＰＤ组（Ｐ＜０．０１）。胸片，胸部ＣＴ，ＣＥＡ，β２－Ｍ，ＳＦ和ＳＡ各单项阳性率分别为５２．８％，９１．７％，５８．３％，６９．４％，５０．０％和８０．６％。多项指标组合后诊断的特异性，敏感性明显提高。结论几个非侵入性试验组合能提高肺癌诊断的准确性。
Objective To evaluate the value of non-invasive tests in the diagnosis of lung cancer. Methods Chest radiographs, chest computed tomography (CT), serum carcinoembryonic antigen (CEA), β2-microglobulin (β2-M), ferritin (SF), and sialic acid (SA) were used to synchronously detect lung cancer in 36 patients. 30 cases of benign lesions (BPD). Results The levels of CEA, β2-M, SF, and SA in lung cancer group were significantly higher than those in BPD group (P<0.01). The positive rates of chest X-ray, chest CT, CEA, β2-M, SF and SA were 52.8%, 91.7%, 58.3%, 69.4%, 50.0% and 80.6%, respectively. . The specificity and sensitivity of multiple diagnostic indicators are significantly improved. Conclusion Several non-invasive test combinations can improve the accuracy of lung cancer diagnosis.