【定义】结节病为一病因不明性多系统疾患,主要累及青年,而以双侧肺门淋巴结肿大、肺浸润以及眼与皮肤损害为其最常见表现。如在典型的临床和放射线表现之外,还从一个以上系统中查悉广泛的类上皮细胞肉芽肿的组织学证据,则诊断最为确切。提示病情活动的标志是:Kveim-Siltzbach氏皮试阳性、血清血管紧张素转化酶(SACE)水平增高、血钙和尿钙增高、放射性镓的胸内摄取以及支气管肺泡灌洗液的细胞学表现异常等。本病的病程经过和预后与起病方式有关:急性起病者一般都取自限性经过,可望自愈;而起病隐 [Definition] Sarcoidosis is an ill-defined multi-system disorder that mainly affects young people. It is the most common manifestation of bilateral hilar lymph nodes, lung infiltration and eye and skin lesions. Aside from the typical clinical and radiological manifestations, histological evidence of extensive epithelioid cell granulomas is also available from more than one system, the diagnosis is most accurate. Indicators of disease activity are: Kveim-Siltzbach skin test positive, elevated serum levels of angiotensin-converting enzyme (SACE), elevated serum calcium and urinary calcium, radioactive gallium intrathoracic uptake and bronchoalveolar lavage fluid cytology Abnormal and so on. After the course of the disease and prognosis and onset of the disease: Acute onset are generally taken from the limited after, is expected to self-healing; and onset is hidden