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目的 探讨ＣＯＰＤ 患者静息时脉冲振荡法（ＩＯＳ） 测得呼吸阻抗指标与最大运动能力的关系。方法 ３０ 例ＣＯＰＤ 患者先用ＩＯＳ法测定呼吸阻抗值（ 包括共振频率Ｆｒｅｓ、总阻抗Ｚ、中央阻抗Ｒｃｅｎｔｌ、周围阻抗Ｒｐｅｒｉ、电阻Ｒ５ 至Ｒ３５ 、电抗Ｘ５ 至Ｘ３５） 后进行自行车增量运动试验，记录最大运动负荷（ Ｗｍａｘ） 、最大氧耗量（Ｖｍａｘ） 、最大ＣＯ２ 排出量（ＶＣＯ２ｍａｘ） 、最大每分通气量（ＶＥｍａｘ）、最大潮气量（ＶＴｍａｘ） 、最大气急指数（ＤＩ）和最低血氧饱和度（ＳａＯ２ｍｉｎ） ，运动过程中进行脉氧、心率、血压和胸腹运动协同性监测。结果 极量运动时ＶＥｍａｘ 与Ｆｒｅｓ 最相关（ｒ ＝ － ０ ．６７） ，其次与Ｒ５ 和Ｒ２０ 差值（Ｒ５ － Ｒ２０） 、Ｘ１５ 、Ｘ２０ 、Ｘ２５ 和Ｘ３５ 显著相关，与Ｚ、Ｒ５ 、Ｒ１０ 、Ｘ５ 和Ｘ１０ 有一定的相关性；ＶＴｍａｘ 与Ｆｒｅｓ 最相关（ｒ＝ － ０ ．６２），其次与Ｘ１５ 、Ｘ２０ 和Ｘ２５ 显著相关，与Ｒ５ 和Ｒ１０ 有一定的相关；ＳａＯ２ｍｉｎ 主要与Ｆｒｅｓ、Ｒ５ 和Ｘ２０ 相关（ｒ 均为０ ．４３） ；极量运动时胸腹呼吸运动总和与潮气量的比值（ＴＣＤ／ＶＴ）与Ｒ１０ 有一定的相
Objective To investigate the relationship between the index of respiratory resistance and maximum exercise capacity measured by resting pulse oscillation (IOS) at COPD patients. Methods Thirty patients with COPD were subjected to incremental exercise test with IOS to measure the respiration resistance (including the resonance frequency Fres, the total impedance Z, the central impedance Rcentl, the surrounding impedance Rperi, the resistance R5 to R35, the reactance X5 to X35) Maximum Wmax, Vmax, VCO2max, VEmax, VTmax, DI and minimum oxygen saturation Degree (SaO2min), during exercise pulse oxygen, heart rate, blood pressure and chest and abdomen movement coordination monitoring. Results VEmax was most correlated with Fres (r = - 0.67) during maximal exercise, followed by a significant correlation with R5 and R20 differences (R5 - R20), X15, X20, X25 and X35 and with Z, R5, R10, And X10. VTmax was the most correlated with Fres (r = - 0.62), followed by X15, X20 and X25, and had some correlation with R5 and R10. SaO2min was mainly associated with Fres, R5 and X20 (R = 0.43). The ratio of total chest and abdomen respiratory activity to tidal volume (TCD / VT) during extreme exercise had a certain phase with R10