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目的:探讨多胎妊娠与小儿脑性瘫痪发生的相关性。方法:2002年8~10月对湘潭地区通过流行病学调查了解多胎妊娠脑性瘫痪的患病率和相关危险因素。结果:调查0~7岁儿童179895人,确诊为小儿脑性瘫痪385例,患病率2·14‰。其中双胎850例,确诊小儿脑性瘫痪16例,患病率18·82‰;三胞胎96例,确诊小儿脑性瘫痪为9例,患病率93·75‰。患病率之比三胞胎:双胞胎:单胎=43·08:8·19:1,经统计学处理,妊娠胎数与脑瘫发生率呈指数线性关系,R2=0·99,接近于1,b=0·835>0,表明妊娠胎数与脑瘫患病率高度正相关。结论:多胎妊娠小儿脑性瘫痪患病率较单胎显著增高,加强多胎妊娠的围产期保健工作,可以减少小儿脑性瘫痪患病率。
Objective: To investigate the relationship between multiple pregnancy and cerebral palsy in children. Methods: From August to October in 2002, epidemiological investigation was conducted in Xiangtan to investigate the prevalence and related risk factors of cerebral palsy in multiple pregnancies. Results: 179895 children aged 0-7 years were investigated. 385 children with cerebral palsy were diagnosed with the prevalence of 2.14 ‰. Among them, there were 850 cases of twins and 16 cases of pediatric cerebral palsy diagnosed, with a prevalence of 18.82%; 96 cases of triplets, and 9 cases of pediatric cerebral palsy diagnosed with a prevalence of 93.75%. The prevalence of triplets: twins: singleton = 43.88: 8.19: 1, after statistical treatment, gestational births and the incidence of cerebral palsy showed an exponential linear relationship, R2 = 0.99, close to 1 , b = 0 · 835> 0, indicating that the number of pregnancies is positively correlated with the prevalence of cerebral palsy. Conclusion: The prevalence of cerebral palsy in children with multiple gestations is significantly higher than that of singletons. Strengthening perinatal health care in multiple pregnancies can reduce the prevalence of cerebral palsy in children.